Use 65-70 mph if you want mileage while not being a road block. And yes, 40psi is about the sweet spot for most tires between MPG and harshness.
75mph = low-mid 30's mpg
70mph = mid-high 30's mpg
65mph = 40-ish mpg
60mph = 45-ish mpg
If you wanted good MPG on gas, you shoulda got a standard hybrid.
-Charlie